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Test Code LAPAN LUPUS ANTICOAGULANT PANEL

Additional Codes

Software                                    Test Code                                      
Label Text LAPAN
EPIC LAB20118

Performing Laboratory

NorDx Laboratories

Useful For

The detection of lupus anticoagulant in a patient with a prolonged PTT result.

 

Panel includes:

Drvvt screen

Drvvt confirmation

Hematocrit

INR, plasma

Interpretation

Partial thromboplastin time (PTT), plasma

Silica clot time confirmation

Silica clot time screen

 

If lupus anticoagulant screen is abnormal, the following tests will be performed at an additional charge:

Drvvt confirmation assay

Drvvt mixing assay

Silica mixing study

PTT using reagent more sensitive to factor deficiencies (dade actin FS)

Thrombin time

If the thrombin time is greater than 30 seconds, a Reptilase time test will be performed.

Method Name

Clot-Based Assay

Reference Values

An interpretive report will be issued

Days and Times Test Performed

1 day weekly

Report Available

14 Days

Specimen Type

Submit all of the following:

~ Plasma

~ Whole Blood

Preferred Container

Lavender Top Tube (EDTA)

Light Blue Top Tube (Sodium Citrate) – 3 Tubes – each must be full at time of collection.

Specimen Collection and Handling

BOTH CITRATED PLASMA AND EDTA WHOLE BLOOD ARE REQUIRED.

 

BLUE TOP TUBES:

Collect specimen as follows:

1. Draw blood in 3 light blue-top (3.2% sodium citrate) tube(s). Tube(s) must be full upon collection.

2. Separate plasma from cells as soon as possible within 4 hours of collection in a centrifuge at 2,500 rpm for 15 minutes or 3,000 rpm for 10 minutes.

3. Using a plastic transfer pipette (do not use a glass pipette) decant the plasma to a screw-capped, plastic (polypropylene) vial. Glass vials will not be accepted.

4. Spin the plasma again at 2,500 rpm for 15 minutes or 3,000 rpm for 10 minutes. Note: Double spinning the specimen ensures platelet poor plasma (<10,000 uL)

5. Divide the plasma into as many 0.5-1.0 mL aliquots as possible and cap the vial(s) tightly.

6. Place tubes upright and flash freeze specimen(s) immediately at ≤ – 20° C or below.

7. Send specimen(s) FROZEN on dry ice.

Click here to view the Procedure for Collecting a Specimen from an A-line

 

LAVENDER TOP TUBE:

Mix sample well and send a minimum of 1mL of EDTA whole blood refrigerated.

Sample to be used for a hematocrit result that is run at no charge and will be non-reportable (rule out abnormal results due to hematocrit >55%).

If a high hematocrit is detected the client will be contacted to determine the need for a recollect in properly adjusted blue top tubes. A coagulation pathologist will assess this need with the client.

Specimen Stability Information

Specimen Type: Plasma

Room Temp: 4 Hours

Note: Whole blood that remains capped and unspun is stable for up to 4 hours when stored at room temperature (18 – 24°C). Frozen plasma is stable 2 weeks @ -20°C and 12 months @ -70°C. Blue top tubes for coag assays must not be refrigerated or placed on ice.

Specimen Type: Whole Blood

Refrigerated: 24 Hours

Add On Capable

Yes – if testing is added before the specimen is past 4 hour stability limit at room temperature. Add on testing also possible if plasma is still available frozen @ -70. Please contact the Bramhall Special Coagulation Laboratory to verify that frozen plasma is still available to perform the request.

Advance Beneficiary Notice Requirements

This test, when ordered on Medicare patients, is subject to the National Coverage Determination (NCD) policies. Please verify that the diagnosis code (ICD code) you have chosen demonstrates medical necessity for the test as documented in the physician’s patient record. The CMS web site is available to assist you with this verification. A properly executed Advance Beneficiary Notice (ABN) must be submitted with the specimen if medical necessity is not demonstrated by the ICD code chosen.

CPT Code Information

CPT Code

CPT Description

CPT Disclaimer

84285 Assay of Silica, Quantitative  
84285 Assay of Silica, Quantitative if Indicated
84285-59 Assay of Silica, Quantitative  
85610 Prothrombin Time  
85613 Russell Viper Venom Time (Includes Venom); Diluted  
85613 Russell Viper Venom Time (Includes Venom); Diluted  
85613 Russell Viper Venom Time (Includes Venom); Diluted if Indicated
85635 Reptilase Test if Indicated
85670 Thrombin Time, Plasma if Indicated
85730 Thromboplastin Time, Partial (PTT), Plasma or Whole Blood  
85730 Thromboplastin Time, Partial (PTT), Plasma or Whole Blood if Indicated

Keywords

LUPUS ANTICOAGULANT

LUPUS INHIBITOR

PARTIAL THROMBOPLASTIN TIME (PTT)

PT (PROTHROMBIN TIME)

VENOM TIME, PLASMA

Performing Laboratory Location

NorDx Laboratories

Rejection Information

Underfilled (<90%), clotted, or grossly hemolyzed. If a high hematocrit is detected the client will be contacted to determine the need for a recollect in properly adjusted blue top tubes.