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Test Code VALPR VALPROIC ACID, SERUM OR PLASMA

Performing Laboratory

NorDx Laboratories

Useful For

Monitoring therapy, assessing compliance, and evaluating potential toxicity while receiving valproic acid treatment

Clinical Significance

Valproic acid is used for treatment of simple and complex absence seizures and as combination therapy with any of the other anticonvulsants for control of generalized seizures that include absence seizures.

Method Name

Immunoassay (IA)

Reference Values

Therapeutic concentration:
50-100 ug/mL

Psychiatric use: 50-125 ug/mL

Toxic concentration: >200 ug/mL

Days and Times Test Performed

Monday through Sunday

Report Available

1 Day

Available Stat

Specimen Type

Submit one of the following:

~ Plasma (Maine Medical Center Only)

~ Serum

Preferred Container

Plasma Separator Tube (PST) (Maine Medical Center Only)

Serum Separator Tube (SST)

Preferred Volume

Plasma: 0.5 mL (Plasma Separator Tube (PST)) (Maine Medical Center Only)

Serum: 0.5 mL (Serum Separator Tube (SST))

Minimum Volume

Plasma: 0.3 mL (Plasma Separator Tube (PST))

Serum: 0.3 mL (Serum Separator Tube (SST))

Specimen Collection and Handling

Spin specimen, separate from clot and send refrigerated.

Specimen Stability Information

Specimen Type: Plasma

Frozen: 3 Months

Refrigerated: 2 Days

Must be spun/separated within: 2 Hours

Note: Freeze at-20 for long term storage

Specimen Type: Serum

Frozen: 3 Months

Refrigerated: 2 Days

Must be spun/separated within: 2 Hours

Note: Freeze at-20 for long term storage

Add On Capable

Yes

Advance Beneficiary Notice Requirements

No ABN Required

CPT Code Information

CPT Code

CPT Description

CPT Disclaimer

80164 Drug Assay, Valproic Dipylacetic Acid, Total

Acceptable Alternative Container(s)

Red Top Tube

LOINC Code Information

4086-5

Keywords

DEPAKENE® (VALPROIC ACID)

DEPAKOTE® (VALPROIC ACID)

Performing Laboratory Location

NorDx Laboratories