THYROPEROXIDASE (TPO) ANTIBODIES, SERUM

Additional Codes

Software	Test Code
Label Text	TPOAB
EPIC	LAB858

Performing Laboratory

NorDx Laboratories

Useful For

Diagnosing and managing a variety of thyroid disorders, including autoimmune thyroiditis, Hashimoto’s thyroiditis, Graves’ disease, certain types of goiter, and polyendocrine auto-immunopathies

Method Name

Enzyme Linked Immunosorbent Assay (ELISA)

Reference Values

Negative: 0 - 100 IUmL

Positive: > 100 IU/mL

The presence of immune complexes or other immunoglobulin aggregates in the patient sample may cause an increased level of non-specific binding and produce a false positive in this assay.

A negative result indicates no thyroid peroxidase antibody or levels below the negative cut-off of the assay. A positive result indicates the presence of thyroid peroxidase antibodies and suggests the possibility of Hashimoto’s Thyroiditis and/or Graves’ Disease

Days and Times Test Performed

Monday and Thursday, excluding some holidays

Report Available

Up to 5 days

Specimen Type

Serum

Preferred Container

Serum Separator Tube (SST)

Preferred Volume

Serum: 1 mL (Serum Separator Tube (SST))

Minimum Volume

Serum: 0.5 mL (Serum Separator Tube (SST))

Specimen Collection and Handling

1. Spin specimen, separate from clot and send refrigerated.

2. If delivery to lab is greater than 48 hours, send frozen.

Specimen Stability Information

Specimen Type: Serum

Frozen: 3 Months

Refrigerated: 48 Hours

Acceptable Alternative Container(s)

Red Top Tube

Add On Capable

Yes

CPT Code Information

CPT Code	CPT Description	CPT Disclaimer
86376	Microsomal Antibodies (eg: Thyroid or Liver-Kidney), Each

Performing Laboratory Location