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Test Code SISP2 / 017270-LC Serum Integrated Screen Part 2

Important Note

This test may require pre-authorization or have limited coverage.  Please check with your appropriate insurance carrier to determine any specific requirements.

This series must be matched with Serum Integrated Screen Part 1 (SINT12 / 017200-LC) to complete patient testing

Additional Codes

Software Test Code
Label Text SISP2
EPIC LAB20411                                     
Integrated Genetics               017270

Performing Laboratory

Integrated Genetics (LabCorp Specialty Testing Group)

Useful For

Screening test for open neural tube defects, Down syndrome, and trisomy 18.

This testing does not require an ultrasound.

Method Name

Chemiluminescent Immunoassay (CIA)

Specimen Type

Serum

Preferred Container

Serum Separator Tube (SST)

Preferred Volume

Serum: 5 mL (Serum Separator Tube (SST)) – Specimen requirement for serum, not whole blood.

Minimum Volume

Serum: 3 mL (Serum Separator Tube (SST))

Specimen Collection and Handling

Testing is provided from 15w0d to 21w6d weeks of gestation.

Collect in serum separator tube with gel barrier. Allow blood to clot, avoiding hemolysis. Centrifuge SST tube, separating serum from cells. Transport spun SST tube to testing laboratory. Pouring off serum is not preferred. Maternal serum specimens must be drawn prior to amniocentesis to avoid contamination with fetal blood.

Specimen Stability Information

Specimen Type: Serum

Frozen: 14 Days

Refrigerated: 14 Days

Room Temp: 7 Days

Note: Freeze/thaw cycles: Stable x3

Add On Capable

Not Permitted

CPT Code Information

CPT Code

CPT Description

CPT Disclaimer
81511 Fetal congenital abnormalities, biochemical assays  

Rejection Information

Gross hemolysis, gross lipemia, quantity not sufficient for analysis, improper specimen type .