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Test Code PRION 14-3-3 PROTEIN TAU/THETA, CSF

Important Note

Infectious Disease protocol needs to be followed. All staff (clinical and laboratory) must include supervisor/manager prior to ordering or processing.

Performing Laboratory

Case Western University

Method Name

Enzyme Linked Immunosorbent Assay (ELISA)

Quaking-Induced Conversion

Western Blot (WB)

Reference Values

An interpretive report will be issued

Days and Times Test Performed

Varies

Report Available

7-17 days from arrival at performing laboratory

Specimen Type

Cerebrospinal Fluid (CSF)

Preferred Container

Standard Aliquot Tube

Preferred Volume

Cerebrospinal Fluid (CSF): 5 mL (Standard Aliquot Tube)

Minimum Volume

Cerebrospinal Fluid (CSF): 2 mL (Standard Aliquot Tube)

Specimen Collection and Handling

Transfer CSF to a standard aliquot tube with a screw top and freeze immediately. Transport on dry-ice.

NOTE: A Case Western Test Request Form is REQUIRED to be filled out and sent with specimen.

Specimen Stability Information

Specimen Type: Cerebrospinal Fluid (CSF)

Room Temp:  48 hours

Refrigerated:  2 weeks

Frozen:  Indefinitely

Add On Capable

Yes

CPT Code Information

CPT Code

CPT Description

CPT Disclaimer

0035U Neurology (prion disease), cerebrospinal fluid, detection of prion protein by quaking-induced conformation conversion, qualitative  
84182 Western Blot, with interpretation and report, blood or other body fluid, immunological probe for band identification, each  
86317 Immunoassay for Infectious Agent Antibody, Quantitative, Not Otherwise Specified  

Keywords

Real Time Quake Assay

CJD

Creutzfeldt-Jakob Disease

Human Prion Disease