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Test Code POCKT / 202-AD Karyotype Products of Conception

Additional Codes

Software Test Code
SoftID                                                  POCKT                                                                   
EPIC LAB20421
Allele Diagnostics 202-AD

Performing Laboratory

Allele Diagnostics

Useful For

Chromosome analysis by karyotype. Karyotype can identify numeric chromosomal abnormalities, large unbalanced and balanced structural abnormalities. Abnormalities larger than approximately 5-10 Mb can be visualized. Karyotype is useful in conjunction with microarray to identify balanced abnormalities, such as translocations and inversions, that microarray is not designed to detect. Standard blood karyotype study involves counting 20 cells, analyzing 5 cells, and karyotyping 3 cells. Additional cells are evaluated as indicated if mosaicism is suspected.

Method Name

Chromosome Analysis

Report Available

Turnaround time: 3-4 weeks.

Specimen Type

~ Amniotic Fluid

~ Products of Conception in Sterile Media (Preferred) or Sterile Saline – Sterile RPMI media is preferred.

Preferred Container

Sterile IATA-Approved Screw-Capped Plastic Container

Sterile IATA-Approved Screw-Capped Plastic Container

Preferred Volume

Amniotic Fluid: 20 mL (Sterile IATA-Approved Screw-Capped Plastic Container)

Products of Conception in Sterile Media (Preferred) or Sterile Saline: 20 mg (Sterile IATA-Approved Screw-Capped Plastic Container)

Minimum Volume

Amniotic Fluid: 15 mL (Sterile IATA-Approved Screw-Capped Plastic Container)

Products of Conception in Sterile Media (Preferred) or Sterile Saline: 5 mg (Sterile IATA-Approved Screw-Capped Plastic Container)

Specimen Collection and Handling

Specimens should be shipped at room temperature in a leak-proof, rigid container with overnight delivery.

Add On Capable

Contact Histology Department

CPT Code Information

CPT Code

CPT Description

CPT Disclaimer
88233 Tissue culture for Non-neoplastic Disorders, Skin or Other Solid Tissue Biopsy  
88235 Tissue Culture, Placenta  
88262 Chromosome Analysis, Count 15-20 Cells, 2 Karyotypes, with Banding  
88267 Chromosome Analysis, Placenta  
88269 Chromosome Analysis, Amniotic  
88280 Chromosome karyotype study  

Keywords

Chromosome Analysis

POC

Chorionic villus sampling (CVS)

Clinical Significance

Abnormal fetal ultrasound findings consistent with a trisomy phenotype.

Patients with a known or suspected family history of a chromosome abnormality detectable by karyotype.

Abnormal maternal serum screen.

Previous pregnancy with aneuploidy.

Fetal Loss/Stillborn.

LOINC Code Information

35129-6