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HelpTest Code MTX METHOTREXATE, SERUM
Additional Codes
| Software | Test Code |
|---|---|
| Label Text | MTX |
| EPIC | LAB481 |
Performing Laboratory
NorDx Laboratories
Useful For
Monitoring Methotrexate level in serum
Method Name
Fluorescence Polarization Immunoassay (FPIA)
Reference Values
No therapeutic range has been established.
Serum concentrations of methotrexate are commonly monitored during high-dose therapy (> 50 mg/m2) to identify the time at which active intervention by leucovorin rescue should be initiated. Criteria for serum concentrations indicative of a potential for toxicity after single-bolus, high-dose therapy are as follows:
> 10.0 µmol/L at 24 hours after dose
> 1.0 µmol/L at 48 hours after dose
> 0.1 µmol/L at 72 hours after dose
During high dose regimens methotrexate levels may reach concentrations > 1,000 µmol/L.
Days and Times Test Performed
Monday through Sunday
Report Available
1 Day
Specimen Type
Serum
Preferred Container
Red Top Tube only
Preferred Volume
Serum: 2 mL (Red Top Tube)
Minimum Volume
Serum: 0.5 mL (Red Top Tube)
Specimen Collection and Handling
1. Spin specimen, separate from clot and send refrigerated.
2. Label ALL aliquots: “Serum From Red Top Tube”
Specimen Stability Information
Specimen Type: Serum
Frozen: 3 Months
Refrigerated: 7 Days
Must be spun/separated within: 2 Hours
Add On Capable
Yes
Advance Beneficiary Notice Requirements
No ABN Required
CPT Code Information
|
CPT Code |
CPT Description |
CPT Disclaimer |
|---|---|---|
| 80204 | Methotrexate |
Performing Laboratory Location
NorDx Laboratories
LOINC Code Information
14836-1
Rejection Information
Collected in serum gel tube