Test Code MBCSF / 123377-LC MYELIN BASIC PROTEIN (MBP), CSF
Additional Codes
Software | Test Code |
---|---|
SoftID | MBCSF |
EPIC | LAB190 |
LabCorp | 123377 |
Performing Laboratory
Laboratory Corporation of America (LabCorp)
Useful For
Assisting in diagnosing multiple sclerosis; determine whether an MS patient is having an active demyelinating episode; determine whether active demyelination is occurring in patients being treated by intrathecal chemotherapy or radiation therapy for neoplastic diseases involving the central nervous system; diagnose acute brain tissue destruction in children, including newborns; assess the efficacy of potential treatments for MS
Method Name
Enzyme Linked Immunosorbent Assay (ELISA)
Reference Values
0.0-1.2 ng/mL
Specimen Type
Cerebrospinal Fluid (CSF)
Preferred Container
Screw-Capped Plastic Container – when oligoclonal banding is ordered along with myelin basic protein, the minimum volume of CSF is 0.9 mL
Preferred Volume
Cerebrospinal Fluid (CSF): 1 mL (Screw-Capped Plastic Container)
Minimum Volume
Cerebrospinal Fluid (CSF): 0.8 mL (Screw-Capped Plastic Container)
Specimen Collection and Handling
Centrifuge CSF at 1500xg for 20 minutes and place the supernatant in a separate tube. Ensure that residual fibrin and cellular matter have been removed prior to transport.
Lumbar puncture should be performed within five days of onset of neurologic symptoms suggestive of multiple sclerosis.
Specimen Stability Information
Specimen Type: Cerebrospinal Fluid (CSF)
Frozen: 14 Days
Refrigerated: 14 Days
Room Temp: 14 Days
Note: Stable x3 freeze/thaw cycles.
Add On Capable
Contact Reference Lab – If add-on can never be done, report the test to the Administrative Analyst
Performing Laboratory Location
Laboratory Corporation of America (LabCorp)
Rejection Information
Lipemic, hemolyzed, or icteric specimen