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Test Code MBCSF / 123377-LC MYELIN BASIC PROTEIN (MBP), CSF

Additional Codes

Software                                    Test Code                                      
SoftID  MBCSF
EPIC LAB190
LabCorp 123377

Performing Laboratory

Laboratory Corporation of America (LabCorp)

Useful For

Assisting in diagnosing multiple sclerosis; determine whether an MS patient is having an active demyelinating episode; determine whether active demyelination is occurring in patients being treated by intrathecal chemotherapy or radiation therapy for neoplastic diseases involving the central nervous system; diagnose acute brain tissue destruction in children, including newborns; assess the efficacy of potential treatments for MS

Method Name

Enzyme Linked Immunosorbent Assay (ELISA)

Reference Values

0.0-1.2 ng/mL

Specimen Type

Cerebrospinal Fluid (CSF)

Preferred Container

Screw-Capped Plastic Container – when oligoclonal banding is ordered along with myelin basic protein, the minimum volume of CSF is 0.9 mL

Preferred Volume

Cerebrospinal Fluid (CSF): 1 mL (Screw-Capped Plastic Container)

Minimum Volume

Cerebrospinal Fluid (CSF): 0.8 mL (Screw-Capped Plastic Container)

Specimen Collection and Handling

Centrifuge CSF at 1500xg for 20 minutes and place the supernatant in a separate tube. Ensure that residual fibrin and cellular matter have been removed prior to transport.

Lumbar puncture should be performed within five days of onset of neurologic symptoms suggestive of multiple sclerosis.

Specimen Stability Information

Specimen Type: Cerebrospinal Fluid (CSF)

Frozen: 14 Days

Refrigerated: 14 Days

Room Temp: 14 Days

Note: Stable x3 freeze/thaw cycles.

Add On Capable

Contact Reference Lab – If add-on can never be done, report the test to the Administrative Analyst

Performing Laboratory Location

Laboratory Corporation of America (LabCorp)

Rejection Information

Lipemic, hemolyzed, or icteric specimen