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Test Code IODCU / IODCU-M Iodine/Creatinine Ratio, Random, Urine

Additional Codes

Software Test Code
SCC SoftID IODCU
EPIC

Lab20562

Mayo Clinic Laboratories IOCDU

 


Ordering Guidance


Due to the significant variation in the rate of excretion over the course of a day, a 24-hour collection is preferred. For more information see UIOD / Iodine, 24 Hour, Urine.



Specimen Required


Patient Preparation: High concentrations of gadolinium and iodine may interfere with inductively coupled plasma mass spectrometry-based metal tests. If either gadolinium- or iodine-containing contrast media has been administered, the specimen should not be collected for at least 96 hours.

Supplies: Urine Tubes, 10 mL (T068)

Collection Container/Tube: Clean, plastic urine collection container

Submission Container/Tube: Plastic, 10-mL urine tube or a clean, plastic aliquot container with no metal cap or glued insert

Specimen Volume: 3 mL

Collection Instructions:

1. Collect a random urine specimen.

2. See Metals Analysis Specimen Collection and Transport for complete instructions.


Secondary ID

610708

Useful For

Assessment of iodine toxicity or recent iodine exposure using a random urine collection

 

Monitoring iodine excretion rate as index of replacement therapy

Profile Information

Test ID Reporting Name Available Separately Always Performed
IODC Iodine/Creat Ratio, U No Yes
CRETR Creatinine, Random, U No Yes

Method Name

IODC: Inductively Coupled Plasma Mass Spectrometry (ICP-MS)

CRETR: Enzymatic Colorimetric Assay

Reporting Name

Iodine/Creat Ratio, Random, U

Specimen Type

Urine

Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 30 days
  Frozen  30 days
  Ambient  14 days

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Clinical Information

Iodine is an essential element for thyroid hormone production.

 

The measurement of urinary iodine is preferred for assessment of toxicity, recent exposure, and monitoring iodine excretion rate as an index of replacement therapy.

Reference Values

0-17 years: Not established

≥18 years: <584 mcg/g creatinine

Cautions

Administration of iodine-based contrast media and drugs containing iodine, such as amiodarone, will yield elevated results.

Method Description

The metal of interest is analyzed by inductively coupled plasma mass spectrometry.(Unpublished Mayo method)

Day(s) Performed

Tuesday, Friday

Report Available

2 to 5 days
NorDx Test Catalog Note:

Analytic time for send out tests is the time it will take to perform testing once it has arrived at the performing reference lab. Please add 1 to 2 days from time of collection to allow for receipt at NorDx central lab and shipment of specimen, add another day if specimen is collected on the day before a weekend or holiday.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

83789

82570

LOINC Code Information

Test ID Test Order Name Order LOINC Value
IODCU Iodine/Creat Ratio, Random, U 55928-6

 

Result ID Test Result Name Result LOINC Value
CRETR Creatinine, Random, U 2161-8
614424 Iodine Concentration Interpretation 77202-0
614370 Iodine Concentration 2495-0
610709 Iodine/Creat Ratio, U 55928-6