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Mayo Clinic Laboratories

Test Code IGFBP / 500644-EX INSULIN GROWTH FACTOR-BINDING PROTEIN 3 (IGFBP-3)

Additional Codes

Software Test Code
SoftID                                                  IGFBP                                                                  
EPIC LAB10087
Esoterix 500644

Performing Laboratory

Esoterix Laboratory Services (LabCorp Specialty Testing Group)

Useful For

Diagnosing growth disorders, diagnosing adult growth hormone deficiency, monitoring of recombinant human growth hormone treatment.

A possible adjunct to insulin-like growth factor 1 and growth hormone in the diagnosis and follow-up of acromegaly and gigantism

Method Name

Immunochemiluminometric Assay (ICMA)

Reference Values

An interpretive report will be issued

Days and Times Test Performed

Monday through Friday

Report Available

3-5 Days

Specimen Type

Serum/plasma

Preferred Container

Serum Separator Tube (SST)

Preferred Volume

Serum: 1 mL

Minimum Volume

Serum: 0.1 mL (NOTE:This volume does NOT allow for repeat testing).

Specimen Collection and Handling

Spin specimen, separate serum or plasma from cells within 45 minutes of collection into standard transport aliquot tube. Send to performing reference lab frozen.

Specimen Stability Information

Specimen Type: Serum

Frozen: 90 Days

Refrigerated: 14 Days

Room Temp: 14 Days

Note: Freeze/thaw cycles: Stable x3

Add On Capable

Contact Reference Lab – If add-on can never be done, report the test to the Administrative Analyst

Advance Beneficiary Notice Requirements

This test, when ordered on Medicare patients, is subject to the National Coverage Determination (NCD) policies. Please verify that the diagnosis code (ICD code) you have chosen demonstrates medical necessity for the test as documented in the physician’s patient record. The CMS web site is available to assist you with this verification. A properly executed Advance Beneficiary Notice (ABN) must be submitted with the specimen if medical necessity is not demonstrated by the ICD code chosen.

CPT Code Information

CPT Code

CPT Description

CPT Disclaimer

83519 Analyte other than Infectious Agent Antibody or Infectious Antigen, Quantitative, by Radioimmunoassay  

Performing Laboratory Location

Esoterix Laboratory Services (LabCorp Specialty Testing Group)

LOINC Code Information

2483-6

Acceptable Alternative Container(s)

Red-top tube

Lavender Top Tube (EDTA) – EDTA Plasma