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HelpTest Code HISTB / 012518-LC ANTIHISTONE ANTIBODIES
Additional Codes
| Software | Test Code |
|---|---|
| SoftID | HISTB |
| EPIC | LAB10083 |
| LabCorp | 012518 |
Performing Laboratory
Laboratory Corporation of America (LabCorp)
Useful For
Evaluating patients suspected of having drug-induced Lupus
Method Name
Enzyme Linked Immunosorbent Assay (ELISA)
Reference Values
Negative: <1.0 units
Weak positive: 1.0-1.5 units
Moderate positive: 1.6-2.5 units
Strong positive: >2.5 units
Days and Times Test Performed
Monday through Thursday
Report Available
1 Day
Specimen Type
Serum
Preferred Container
Serum Separator Tube (SST)
Preferred Volume
Serum: 1 mL (Serum Separator Tube (SST))
Minimum Volume
Serum: 0.5 mL (Serum Separator Tube (SST))
Specimen Collection and Handling
Spin specimen, separate from clot and send at ambient temperature.
Specimen Stability Information
Specimen Type: Serum
Frozen: 14 Days
Refrigerated: 14 Days
Room Temp: 14 Days
Add On Capable
Contact Reference Lab – If add-on can never be done, report the test to the Administrative Analyst
Advance Beneficiary Notice Requirements
This test, when ordered on Medicare patients, is subject to the National Coverage Determination (NCD) policies. Please verify that the diagnosis code (ICD code) you have chosen demonstrates medical necessity for the test as documented in the physician’s patient record. The CMS web site is available to assist you with this verification. A properly executed Advance Beneficiary Notice (ABN) must be submitted with the specimen if medical necessity is not demonstrated by the ICD code chosen.
CPT Code Information
|
CPT Code |
CPT Description |
CPT Disclaimer |
|---|---|---|
| 86235 | Extractable Nuclear Antigen, Antibody to, Any Method (eg: nRNP, SS-A, SS-B, Sm, RNP, Sc170, J01), Each Antibody |
Keywords
ANTI-HISTONE AUTOANTIBODIES
AUTOANTIBODIES TO HISTONE
Performing Laboratory Location
Laboratory Corporation of America (LabCorp)
Clinical Significance
Antibodies to histones are detected in approximately 30% to 60% of patients with systemic lupus erythematosus (SLE) however their presence in about 95% of patients with drug-induced lupus is more important diagnostically.
LOINC Code Information
29996-6
Acceptable Alternative Container(s)
Red Top Tube