Test Code HHDNA HEREDITARY HEMOCHROMATOSIS, WHOLE BLOOD

Important Note

This test may require pre-authorization or have limited coverage. Please check with your appropriate insurance carrier to determine any specific requirements.

This test should not be ordered unless the fasting morning transferrin saturation is higher than 45%.

Additional Codes

Software	Test Code
Label Text	HHDNA
EPIC	LAB10258

Performing Laboratory

NorDx Laboratories

Useful For

Diagnosing iron storage disorders

Point mutations C282Y and H63D are probed with both wild and mutant probes to determine zygosity.

Method Name

Real Time-Polymerase Chain Reaction (rt-PCR)

This assay is a lab developed test established by the NorDx Molecular Pathology Laboratory. This laboratory is certified under the Clinical Laboratory Improvement Amendments (CLIA) as qualified to perform high complexity clinical laboratory testing. This test is used for clinical purposes. It should not be regarded as investigational or for research.

Reference Values

Negative for C282Y and/or H63D (reported as negative or positive for C282Y and/or H63 with zygosity)

Days and Times Test Performed

Thursday

Testing performed by department once per week or every other week, varies

Report Available

Up to two weeks

Profile Information

Individual Test Description
HEMOCHROMATOSIS HFE GENE ANALYSIS

Specimen Type

Whole Blood

Preferred Container

Lavender Top Tube (EDTA)

Preferred Volume

Whole Blood: 0.5 mL (Lavender Top Tube (EDTA))

Specimen Collection and Handling

1. Send whole blood refrigerated.

2. Sample must arrive within 5 days of collection.

Specimen Stability Information

Specimen Type: Whole Blood

Refrigerated or Ambient Temperature: 7 Days

Add On Capable

Yes

Advance Beneficiary Notice Requirements

This test, when ordered on Medicare patients, is subject to the National Coverage Determination (NCD) policies. Please verify that the diagnosis code (ICD code) you have chosen demonstrates medical necessity for the test as documented in the physician’s patient record. The CMS web site is available to assist you with this verification. A properly executed Advance Beneficiary Notice (ABN) must be submitted with the specimen if medical necessity is not demonstrated by the ICD code chosen.

CPT Code Information

CPT Code	CPT Description	CPT Disclaimer
81256	HFE (Hemachromatosis) Gene Analysis, Common Variant

Keywords

HEMOCHROMATOSIS

HFE GENE

HLA-H GENE

Performing Laboratory Location