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Test Code FREST / 004614-LC ESTRIOL, FREE, SERUM

Performing Laboratory

Laboratory Corporation of America (LabCorp)

Useful For

Evaluating fetal distress and placental function in the management of patients facing complications such as preëclampsia, fetal growth retardation, diabetes, Rh immunization, choriocarcinoma, and hydatidiform mole

May be elevated in hydrops fetalis in the presence of a dying fetus. May be low in the presence of a living anencephalic fetus.

Method Name

Immunochemiluminometric Assay (ICMA)

Reference Values

GESTATIONAL WEEK MEDIAN CENTRAL 95% RANGE

Week 27: 4.6 ng/mL 2.6-7.1 ng/mL

Week 28: 4.7 ng/mL 2.6-7.8 ng/mL

Week 29: 5.0 ng/mL 2.6-8.6 ng/mL

Week 30: 5.5ng/mL 2.7-9.6 ng/mL

Week 31: 6.1 ng/mL 2.9-11.0 ng/mL

Week 32: 6.9 ng/mL 3.2-12.7 ng/mL

Week 33: 8.0 ng/mL 3.4 to >13.3 ng/mL

Week 34: 9.3 ng/mL 3.7 to >13.3 ng/mL

Week 35: 11.3 ng/mL 4.3 to >13.3 ng/mL

Week 36: >13.3 ng/mL 5.3 to >13.3ng/mL

Week 37: >13.3 ng/mL 6.2 to >13.3 ng/mL

Week 38: >13.3 ng/mL 7.4 to >13.3 ng/mL

Week 39: >13.3 ng/mL 8.1 to >13.3 ng/mL

Week 40: >13.3 ng/mL 8.5 to >13.3 ng/Ml

Days and Times Test Performed

Monday through Friday

Report Available

1-3 Days

Specimen Type

Serum

Preferred Container

Serum Separator Tube (SST)

Preferred Volume

Serum: 1 mL (Serum Separator Tube (SST)) – Note: This 0.3 does not allow for repeat testing.

Minimum Volume

Serum: 0.3 mL (Serum Separator Tube (SST))

Specimen Collection and Handling

1. Spin specimen, separate from clot and send refrigerated.

2. If a red-top tube is used, transfer separated serum to a plastic transport tube.

3. All specimens should be drawn at the same time of day to allow comparison of values.

Specimen Stability Information

Specimen Type: Serum

Frozen: 14 Days

Refrigerated: 14 Days

Room Temp: 14 Days

Note: Stable x3 freeze/thaw cycles

Add On Capable

Contact Reference Lab – If add-on can never be done, report the test to the Administrative Analyst

Advance Beneficiary Notice Requirements

No ABN Required

CPT Code Information

CPT Code

CPT Description

CPT Disclaimer
82677 Estriol, Quantitative

Keywords

E3

PREGNANCY, ESTRIOL

UNCONJUGATED ESTRIOL

Performing Laboratory Location

Laboratory Corporation of America (LabCorp)

LOINC Code Information

2251-7

Acceptable Alternative Container(s)

Red Top Tube

Rejection Information

Plasma specimen