FETAL RED CELL SCREEN RH (Fetal Maternal Screen)

Additional Codes

Software	Test Code
Label Text	FMS
EPIC	LAB10967

Performing Laboratory

NorDx Laboratories

Useful For

A qualitative screening test designed for the detection of RhD-positive fetal red blood cells in RhD-negative women to determine when greater than the standard dose of Rh-Immune Globulin is required to prevent immunization.

NOTE: This test can only be used postpartum for Rh negative mothers when the Rh type of the fetus/newborn is known to be Rh pos. If the Rh type of the fetus/newborn is unknown, a fetal stain (Kleihauer-Betke) must be performed.

Method Name

Red Blood Cell Agglutination (Rosette)

Reference Values

Not applicable

If the fetal screen is positive, a Kleihauer-Betke will automatically be performed. An additional charge will result for this testing, if performed.

Days and Times Test Performed

Monday through Sunday

Report Available

1 Day

Specimen Type

Whole Blood

Preferred Container

Pink Top Tube (EDTA)

Preferred Volume

Whole Blood: 6 mL (Pink Top Tube (EDTA))

Specimen Collection and Handling

1. Collect sample as soon as possible following delivery. Recommend to wait at least one hour following delivery to allow any fetal blood to mix thoroughly in maternal circulation.

2. Send whole blood at ambient temperature.

3. Tube MUST be labelled with full name of patient (Last, First [Do not use nicknames]), date of birth and /or identification number, date of collection, and initials of person drawing specimen.

Specimen Stability Information

Specimen Type	Temperature	Time
Whole Blood	Refrigerated	2 days

Note: Transport at ambient temperature preferred, refrigerated transport acceptable. Do not freeze. Storage Condition: refrigerated (2-8°C).

Add On Capable

No

Advance Beneficiary Notice Requirements

No ABN Required

CPT Code Information

CPT Code	CPT Description	CPT Disclaimer
85461	Hemoglobin or RBCs, Fetal, for Fetomaternal Hemorrhage; Rosette (FMS)
85460	Hemoglobin or RBCs, Fetal, for Fetomaternal Hemorrhage; Differential Lysis (Kleihauer-Betke)	If applicable

LOINC Code Information

33900-2 : Fetal cell screen [Presence] in Blood by Rosette test

Acceptable Alternative Container(s)

Lavender Top Tube (EDTA) – ONLY PRIMARY TUBE SAMPLES WILL BE ACCEPTED FOR TESTING.

Rejection Information

Pink top (EDTA) rejected if tube not labeled with full name of patient (last, first [do not use nicknames]), date of birth and/or identification number, date of collection, and initials of person drawing specimen.

Clinical Significance

The Fetal Red Cell Screen (FMS) is a qualitative screening test designed for the detection of large fetomaternal hemorrhages (FMH) of D-positive fetal cells in D-negative maternal blood samples. If the FMH is larger than 30 mL, more than one 300 µg dose of Rh Immune Globulin (RhIg) will be necessary to prevent the isoimmunization of anti-D. Therefore, all positive FMS should be followed by a quantitative test, such as the Kleihauer-Betke test, to determine if the patient will need additional doses of RhIg.

Keywords

FMS

Performing Location