Test Code ETYGQ / UCETG-MC ETHYL GLUCURONIDE QUANTITATIVE, URINE
Performing Laboratory
Michigan Co-Tenancy Laboratory at Warde Medical Laboratory (MCL)
Useful For
LC/MS/MS confirmation for identification of Ethyl Glucuronide and Ethyl Sulfate in urine.
Method Name
Liquid Chromatography-Tandem Mass Spectrometry (LC-MC/MS)
Reference Values
An interpretive report will be issued
Days and Times Test Performed
Tuesday and Thursday
Report Available
5 Days
Specimen Type
Urine
Preferred Container
Urine Cup
Preferred Volume
Urine: 10 mL (Urine Cup)
Minimum Volume
Urine: 2 mL (Urine Cup)
Specimen Collection and Handling
Collect random urine. Mix well and send 10.0 mL urine (2.0 mL minimum) refrigerated in a screw-capped plastic urine cup.
Specimen Stability Information
Specimen Type: Urine
Frozen: 14 Days
Refrigerated: 14 Days
Room Temp: 2 Days
Add On Capable
Yes
Advance Beneficiary Notice Requirements
This test, when ordered on Medicare patients, is subject to the National Coverage Determination (NCD) policies. Please verify that the diagnosis code (ICD code) you have chosen demonstrates medical necessity for the test as documented in the physician’s patient record. The CMS web site is available to assist you with this verification. A properly executed Advance Beneficiary Notice (ABN) must be submitted with the specimen if medical necessity is not demonstrated by the ICD code chosen.
CPT Code Information
CPT Code |
CPT Description |
CPT Disclaimer |
---|---|---|
80321 | Alcohol Biomarkers, 1 or 2 (Definitive Drug Testing) | |
G0480 | Drug Test (Definitive), 1-7 Classes | Government Payers, if Applicable |
G0481 | Drug Test (Definitive), 8-14 Classes | Government Payers, if Applicable |
G0482 | Drug Test (Definitive), 15-21 Classes | Government Payers, if Applicable |
G0483 | Drug Test (Definitive), 22+ Classes | Government Payers, if Applicable |
Clinical Significance
Ethyl glucuronide can be routinely quantified in urine for about 20 hours after a single drink of an ethanol containing beverage (up to 80 hours after heavy ethanol consumption). Both ethyl glucuronide (ETG) and ethyl sulfate (ETS) are metabolites of ethanol. Detection of ETS confirms that the presence of ETG is not a result of in vitro fermentation of sugars. It is known that bacterial fermentation would generate ETG in vitro, but not ETS. Under normal situation, detection of both metabolites concurrently after alcohol consumption is likely. However, due to the genetic polymorphism in the general population, and/or the timing of the specimen collection after drinking, detection of only one metabolite, either ETG or ETS is possible.
Rejection Information
Urine catheter cup (with needle)
LOINC Code Information
2161-8
45324-1
58715-4
60676-4