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Test Code CYA CYCLOSPORINE, BLOOD

Additional Codes

Software Test Code
Label text CYA
EPIC LAB874

Performing Laboratory

NorDx Laboratories

Useful For

A quantitative measurement of Cyclosporine in whole blood to guide dosage adjustments for optimal immunosuppression while minimizing toxicity

Method Name

Chemiluminescent Microparticle Immunoassay (CMIA)

Reference Values

Recommended Therapeutic Ranges for Neoral Monitoring on 12 hour Trough Samples:

 

Cyclosporine (12 hour TROUGH) for renal transplant:

< 3 months post-transplant: 235 - 310 ng/mL

3 - 12 months post-transplant: 160 - 235 ng/mL

> 12 months post-transplant: 60 - 135 ng/mL

Potentially toxic value: > 400 ng/mL

 

Cyclosporine (12 hour TROUGH) for non-renal transplant:

100 - 400 ng/Ml

Potentially toxic value: > 400 ng/mL

Days and Times Test Performed

Monday through Sunday

Report Available

1 Day

Available Stat

Specimen Type

Whole Blood

Preferred Container

Lavender Top Tube (EDTA)

Preferred Volume

Whole Blood: 4.0 mL (Lavender Top Tube (EDTA))

Minimum Volume

Whole Blood: 0.3 mL (Lavender Top Tube (EDTA))

Specimen Collection and Handling

Send whole blood refrigerated in primary collection tube. Do not centrifuge sample.

Specimen Stability Information

Specimen Type: Whole Blood

Frozen: 3 Months

Refrigerated: 7 Days

Add On Capable

Yes

Advance Beneficiary Notice Requirements

No ABN Required

CPT Code Information

CPT Code

CPT Description

CPT Disclaimer

80158 Drug Assay, Cyclosporine  

Performing Laboratory Location

NorDx Laboratories

LOINC Code Information

3520-4

Clinical Significance

Therapeutic ranges apply to trough specimens collected just prior to a.m. dose.
Peak ranges apply to peak specimens collected 2 hours post dose.

Keywords

NEORAL

SANDIMMUNE® (CYCLOSPORINE)