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General Information:

 

Top 3 Reference Laboratory Test Catalogs for Miscellaneous Lab Test Orders:

 

Specimen Collection Information:

Reference Intervals:

System-Wide MaineHealth Laboratory Reference Intervals (Common tests only)

 

Critical Values:

System-Wide MaineHealth Laboratory Critical Values

Mayo Clinic Laboratories

Test Code BENZO BENZODIAZEPINES SCREEN WITH LC-MS/MS CONFIRMATION,URINE

Important Note

Does not detect Zolpidem (Ambien). Please order a reference miscellaneous lab test for Zolpidem.

Additional Codes

Software Test Code
Label Text BENZO
EPIC LAB10890

Performing Laboratory

NorDx Laboratories

Useful For

Detecting benzodiazepines and their metabolites in urine

Method Name

Enzyme Immunoassay (EIA)

Gas Chromatography-Mass Spectrometry (GC-MS) (If indicated)

Reference Values

Not Detected

 

EIA cutoff concentration 200 ng/mL

 

LC-MS/MS cutoff concentrations:

Lorazepam: < 40 ng/mL

Nordiazepam: < 40 ng/mL

Oxazepam: < 40 ng/mL

Temazepam: < 40 ng/mL

Hydroxyethyl-flurazepam: < 40 ng/mL

7-Amino-clonazepam: < 40 ng/mL

Alpha-hydroxyalprazolam: < 20 ng/mL

 

For help with interpretation please call: 877-323-0045

 

Please see test code BENUR for additional benzodiazepine confirmatory testing information.

Days and Times Test Performed

Monday through Friday

Report Available

1 Day

If Negative

Specimen Type

Urine, Random

Preferred Container

Urine Cup

Preferred Volume

Urine, Random: 25 mL (Urine Cup)

Minimum Volume

Urine, Random: 10 mL (Urine Cup)

Specimen Collection and Handling

Collect random urine and send refrigerated in a clean, non-sterile urine container.

Add On Capable

Not Permitted

Advance Beneficiary Notice Requirements

This test, when ordered on Medicare patients, is subject to the National Coverage Determination (NCD) policies. Please verify that the diagnosis code (ICD code) you have chosen demonstrates medical necessity for the test as documented in the physician’s patient record. The CMS web site is available to assist you with this verification. A properly executed Advance Beneficiary Notice (ABN) must be submitted with the specimen if medical necessity is not demonstrated by the ICD code chosen.

CPT Code Information

CPT Code

CPT Description

CPT Disclaimer
80307 Drug Test, Presumptive Screening, By Instrument Chemistry (i.e Immunoassay, Chromatography, and Mass Spectrometry)  
80346 Benzodiazepines, 1-12 (Definitive), Quantitative if Indicated
G0480 Drug Test (Definitive), 1-7 Classes Government Payers, if Applicable
G0481 Drug Test (Definitive), 8-14 Classes Government Payers, if Applicable
G0482 Drug Test (Definitive), 15-21 Classes Government Payers, if Applicable
G0483 Drug Test (Definitive), 22+ Classes Government Payers, if Applicable

Performing Laboratory Location

NorDx Laboratories

LOINC Code Information

14316-4

Clinical Significance

If the benzodiazepine screen is ≥ 200 ng/mL, the benzodiazepine confirmation/quantitation by LC-MS/MS is performed at an additional charge.

 

Specific gravity, pH, creatinine and oxidants will be performed and reported at no additional charge to identify potential adulteration of the urine specimen.

 

INTENDED POSITIVES:

Alprazolam (Xanax)

Chlordiazepoxide (Librium, Librax)

Clonazepam (Klonopin)

Clorazepate (Tranxene)

Diazepam (Diastat, Valium)

Flunitrazepam (Rohypnol, Roofies)

Flurazepam (Dalmane)

Lorazepam (Ativan)

Oxazepam (Serax)

Temazepam (Restoril)

Triazolam (Halcion)

Maximum Laboratory Time

3 Days

Keywords

DRUGS OF ABUSE