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Test Code B12 VITAMIN B12 ASSAY, SERUM

Additional Codes

Software Test Code
SoftID B12
EPIC LAB67

Performing Laboratory

NorDx Laboratories

Useful For

Detecting B12 deficiencies due to low vitamin B12 intake, malabsorption, or abnormalities associated with altered B12 transport into the body; aiding in the diagnosis of megaloblastic anemia and certain neurological abnormalities

Clinical Significance

No sample should be collected on patients receiving therapy with high biotin doses (i.e. biotin therapy for Multiple Sclerosis or oncology patients; skin, hair and nail supplements, or multivitamins containing > 5 mg/day) until at least 12 hours after the last biotin administration. If unsure, or if the clinical picture does not fit the results please contact the laboratory . We have methods to check for biotin interference as well as for any other interferences and for the accuracy of the results.

Biotin interference would falsely increase the result of this assay.

Method Name

Electrochemiluminescent Immunoassay (ECLIA)

Reference Values

232 – 1245 pg/mL

Days and Times Test Performed

Monday through Sunday

Report Available

1 Day

Specimen Type

Serum

Preferred Container

Serum Separator Tube (SST)

Preferred Volume

Serum: 1 mL (Serum Separator Tube (SST))

Minimum Volume

Serum: 0.5 mL (Serum Separator Tube (SST))

Specimen Collection and Handling

1. Spin down, separate from clot and send refrigerated.

2. Sample should not be collected from patients receiving therapy with high biotin doses (i.e. >5 mg/day) until at least 8 hours after the last biotin administration.

Specimen Stability Information

Specimen Type: Serum

Frozen: 2 Months

Refrigerated: 2 Days

Must be spun/separated within: 2 Hours

Note: Avoid prolonged exposure to light (normal storage in walk-in refrigerator is acceptable).

Add On Capable

Yes

Advance Beneficiary Notice Requirements

No ABN Required

CPT Code Information

CPT Code

CPT Description

CPT Disclaimer

82607 Cyanocobalamin (Vitamin B-12), Quantitative  

Acceptable Alternative Container(s)

Red Top Tube

LOINC Code Information

2132-9

Keywords

B12 ASSAY

COBALAMIN

CYANOCOBALAMIN

PTEROYLGLUTAMIC ACID

Performing Laboratory Location

NorDx Laboratories